Title: Diethadione
CAS Registry Number: 702-54-5
CAS Name: 5,5-Diethyldihydro-2H-1,3-oxazine-2,4(3H)-dione
Additional Names: 5,5-diethyl-2,3,5,6-tetrahydro-4H-1,3-oxazine-2,4-dione
Trademarks: Dioxone; Ledosten; Persisten; Tocèn (Lepetit)
Molecular Formula: C8H13NO3
Molecular Weight: 171.19
Percent Composition: C 56.13%, H 7.65%, N 8.18%, O 28.04%
Literature References: Prepn: Testa et al., J. Org. Chem. 24, 1928 (1959); GB 855244 (1960 to Lepetit, SpA). Toxicity study: Maffii et al., J. Pharm. Pharmacol. 13, 244 (1961).
Properties: Crystals from ether, mp 97-98°. LD50 in mice, rats (mg/kg): 52, 31.6 i.p.; 130, 70.5 orally (Maffii).
Melting point: mp 97-98°
Toxicity data: LD50 in mice, rats (mg/kg): 52, 31.6 i.p.; 130, 70.5 orally (Maffii)
Therap-Cat: Analeptic.
Keywords: Anticonvulsant.
Status: This monograph has been retired and is no longer subject to revision or update. |