Title: Potassium p-Aminobenzoate
CAS Registry Number: 138-84-1
CAS Name: p-Aminobenzoic acid potassium salt
Additional Names: potassium para-aminobenzoate; KPABA
Trademarks: Potaba (Glenwood)
Molecular Formula: C7H6KNO2
Molecular Weight: 175.23
Percent Composition: C 47.98%, H 3.45%, K 22.31%, N 7.99%, O 18.26%
Literature References: Prepn: E. A. Meyers et al., J. Am. Chem. Soc. 89, 3565 (1967). Crystal structure: G. S. Ciminago, C.R. Seances Acad. Sci. Ser. C 267, 1402 (1968). Antifibrotic efficacy in idiopathic pulmonary fibrosis: U. H. Cegla et al., Pneumonologie 152, 75 (1975); in Peyronie's disease: A. J. Riley, Br. J. Sex. Med. 6, 29 (1970); G. Williams, N. A. Green, Br. J. Urol. 52, 392 (1980).
Properties: Crystals from alcohol. Saline taste. Slightly alkaline to litmus. pH of 1% soln about 7. Very freely sol in water, less sol in alc. Practically insol in ether. Reported to cause less gastric irritation than the free acid or the sodium salt.
Use: Catalyst in the manuf of condensation polymers of polyglycol ethers.
Therap-Cat: Antifibrotic.
Keywords: Antifibrotic. |