Title: Mephenoxalone
CAS Registry Number: 70-07-5
CAS Name: 5-[(2-Methoxyphenoxy)methyl]-2-oxazolidinone
Additional Names: 5-(o-methoxyphenoxymethyl)-2-oxazolidinone; metoxadone; methoxydon(e); methoxadone
Manufacturers' Codes: AHR-233; OM-518
Trademarks: Dorsiflex (Drossapharm); Control-Om (OM); Xerene (Martinet)
Molecular Formula: C11H13NO4
Molecular Weight: 223.23
Percent Composition: C 59.18%, H 5.87%, N 6.27%, O 28.67%
Literature References: Prepn: Lunsford et al., J. Am. Chem. Soc. 82, 1166 (1960); Lunsford, US 2895960 (1959 to A. H. Robins). Toxicity data: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Determn in pharmaceutical formulations: N. Erk, J. Pharm. Biomed. Anal. 21, 429 (1999).
Properties: Crystals from 95% ethanol, mp 143-145°. Water insol. LD50 orally in rats: 3820 ±17 mg/kg (Goldenthal).
Melting point: mp 143-145°
Toxicity data: LD50 orally in rats: 3820 ±17 mg/kg (Goldenthal)
Therap-Cat: Muscle relaxant (skeletal).
Keywords: Muscle Relaxant (Skeletal). |