Title: CAPS
CAS Registry Number: 1135-40-6
CAS Name: 3-(Cyclohexylamino)-1-propanesulfonic acid
Molecular Formula: C9H19NO3S
Molecular Weight: 221.32
Percent Composition: C 48.84%, H 8.65%, N 6.33%, O 21.69%, S 14.49%
Literature References: One of the zwitterionic amino acids known as "Good" buffers; active in the pH range of 9.7-11.1. Prepn: H. Dorn, K. Walter, Z. Chem. 7, 151 (1967). Thermodynamic parameters: C. D. McGlothlin, J. Jordan, Anal. Lett. 9, 245 (1976). Effects on protein measurement: V. Kaushal, L. D. Barnes, Anal. Biochem. 157, 291 (1986); H. M. Himmel, W. Heller, J. Clin. Chem. Clin. Biochem. 25, 909 (1987). Use as buffer: I. I. Koukli et al., Analyst 113, 603 (1988); R. M. Smith et al., J. Chromatogr. 514, 97 (1990).
Properties: Colorless needles from methanol, mp 302-303°. pK (25°): 10.35.
Melting point: mp 302-303°
pKa: pK (25°): 10.35
Use: Biological buffer. |