Title: Tiaprofenic Acid
CAS Registry Number: 33005-95-7
CAS Name: 5-Benzoyl-a-methyl-2-thiopheneacetic acid
Additional Names: a-methyl-5-benzoyl-2-thienylacetic acid
Manufacturers' Codes: FC-3001; RU-15060
Trademarks: Suralgan (Poli); Surgam (HMR)
Molecular Formula: C14H12O3S
Molecular Weight: 260.31
Percent Composition: C 64.60%, H 4.65%, O 18.44%, S 12.32%
Literature References: Non-steroidal anti-inflammatory. Prepn: F. Clémence, O. Le Martret, DE 2055264 and FR 2112111 (1971 and 1972 to Roussel-UCLAF), C.A. 75, 63597u (1971) and 78, 97473c (1973); F. Clémence et al., Eur. J. Med. Chem. - Chim. Ther. 9, 390 (1974). Pharmacology: eidem, ibid.; H. Fujimura et al., Oyo Yakuri 9, 715 (1975), C.A. 83, 188321w (1975). Review of pharmacology and efficacy in rheumatic diseases and pain control: E. M. Sorkin, R. N. Brogden, Drugs 29, 208-235 (1985).
Properties: mp 96° (isopropyl ether).
Melting point: mp 96° (isopropyl ether)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives. |