Title: Rafoxanide
CAS Registry Number: 22662-39-1
CAS Name: N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
Additional Names: 3¢-chloro-4¢-(p-chlorophenoxy)-3,5-diiodosalicylanilide
Manufacturers' Codes: MK-990
Trademarks: Flukanide (Merck & Co.); Ranide (Merck & Co.)
Molecular Formula: C19H11Cl2I2NO3
Molecular Weight: 626.01
Percent Composition: C 36.45%, H 1.77%, Cl 11.33%, I 40.54%, N 2.24%, O 7.67%
Literature References: Prepn: NL 6815783; BE 724668 (both 1969 to Merck & Co.); Mrozik et al., Experientia 25, 883 (1969). Trials in sheep and cattle: Snijders, Horak, Louw, J. S. Afr. Vet. Med. Assoc. 43, 397 (1972); 44, 251 (1973); 46, 265 (1975); Horak, Snijders, Vet. Rec. 94, 12 (1974).
Properties: Crystals, mp 168-170°. Moderately sol in acetone and acetonitrile. Practically insol in water.
Melting point: mp 168-170°
Therap-Cat-Vet: Fasciolicide; anthelmintic. |