Title: Dibenzyl Chlorophosphonate
CAS Registry Number: 538-37-4
CAS Name: Phosphorochloridic acid bisphenylmethyl ester
Additional Names: benzyl phosphorochloridate; dibenzylchlorophosphate; DBPCl; dibenzylphosphoryl chloride
Molecular Formula: C14H14ClO3P
Molecular Weight: 296.69
Percent Composition: C 56.68%, H 4.76%, Cl 11.95%, O 16.18%, P 10.44%
Literature References: Prepd by adding sulfuryl chloride to dibenzyl phosphite at 17-19° in CCl4 diluent: Atherton et al., J. Chem. Soc. 1948, 1106; by adding chlorine to dibenzyl phosphite in CCl4 at below 0°: Atherton et al., US 2490573 (1949 to Hoffmann-La Roche).
Properties: Thick oil, dec on standing or distillation. Identified by its reaction with ammonia or amines to form corresponding dibenzyl aminophosphonates.
Use: In solns with inert solvents such as chloroform, carbon tetrachloride, benzene and ether for the phosphorylation of nucleosides and amino acids. |