Title: Chlorotrianisene
CAS Registry Number: 569-57-3
CAS Name: 1,1¢,1¢¢-(1-Chloro-1-ethenyl-2-ylidene)tris[4-methoxybenzene]
Additional Names: chlorotris(p-methoxyphenyl)ethylene; tri-p-anisylchloroethylene; tris(p-methoxyphenyl)chloroethylene
Trademarks: Hormonisene (Temis Lostalo); Merbentul (HMR); Tace (HMR)
Molecular Formula: C23H21ClO3
Molecular Weight: 380.86
Percent Composition: C 72.53%, H 5.56%, Cl 9.31%, O 12.60%
Literature References: Prepd by reacting tri-p-anisylethylene or tri-p-anisylethanol with Cl in an inert solvent: Basford and I.C.I., GB 561508 (1944). Synthesis from p-(p-anisoyl)anisole: Shelton, Van Campen, Jr., US 2430891 (1947 to Merrell).
Properties: Crystals from methanol, mp 114-116°. Softens at 108°. uv max (chloroform): 310 nm, (E1%1cm 423); min 278 nm. Practically insol in water. Soly in alcohol: 0.28 g/100 ml; in ether: 3.6 g/100 ml. Also sol in glacial acetic acid, acetone, chloroform, carbon tetrachloride, benzene, vegetable oils.
Melting point: mp 114-116°
Absorption maximum: uv max (chloroform): 310 nm, (E1%1cm 423); min 278 nm
Therap-Cat: Estrogen.
Keywords: Estrogen; Nonsteroidal. |