Title: Sikkimotoxin
CAS Registry Number: 18651-67-7
CAS Name: 3a,4,9,9a-Tetrahydro-4-hydroxy-6,7-dimethoxy-9-(3,4,5-trimethoxyphenyl)naphtho[2,3-c]furan-1(3H)-one
Additional Names: 1-hydroxy-2-hydroxymethyl-6,7-dimethoxy-4-(3¢,4¢,5¢-trimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-3-carboxylic acid lactone
Molecular Formula: C23H26O8
Molecular Weight: 430.45
Percent Composition: C 64.18%, H 6.09%, O 29.74%
Literature References: Isoln from roots and rhizomes of Podophyllum sikkimensis R. Chatterjee et Mukerjee, Berberidaceae: Chatterjee, Datta, Indian J. Physiol. Allied Sci. 4, 61 (1950). Structure: Chatterjee, Chakravarti, J. Am. Pharm. Assoc. Sci. Ed. 41, 415 (1952); Schreier, Helv. Chim. Acta 47, 1529 (1964).
Properties: Crystals from ethanol + benzene, mp 120°. [a]D25 -91.8°. Freely sol in ethanol, methanol, chloroform. Sparingly sol in benzene. Practically insol in water and petr ether.
Melting point: mp 120°
Optical Rotation: [a]D25 -91.8°
Status: This monograph has been retired and is no longer subject to revision or update. |