Title: Pentachlorophenol
CAS Registry Number: 87-86-5
Additional Names: Penta; PCP; penchlorol
Trademarks: Santophen 20 (Monsanto)
Molecular Formula: C6HCl5O
Molecular Weight: 266.34
Percent Composition: C 27.06%, H 0.38%, Cl 66.56%, O 6.01%
Literature References: Prepd by the chlorination of phenol in the presence of a catalyst. Toxicity study: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Review of toxicology and human exposure: Toxicological Profile for Pentachlorophenol (PB2001-109106, 2001) 316 pp.
Properties: Needle-like crystals, mp 190-191°; bp ~309-310° (dec). d422 1.978. Very pungent odor only when hot. Sublimes in needles. Almost insol in water (8 mg in 100 ml). Freely sol in alc, ether; sol in benzene; slightly sol in cold petr ether. LD50 in male, female rats (mg/kg): 146, 175 orally (Gaines).
Melting point: mp 190-191°
Boiling point: bp ~309-310° (dec)
Density: d422 1.978
Toxicity data: LD50 in male, female rats (mg/kg): 146, 175 orally (Gaines)
Derivative Type: Sodium salt
Additional Names: Sodium pentachlorophenate; sodium pentachlorophenoxide
Trademarks: Santobrite (Monsanto); Dowicide G (Dow)
Properties: Sol in water.
CAUTION: Potential symptoms of overexposure are irritation of eyes, nose, throat; sneezing, cough; weakness, anorexia, weight loss; sweating; headache, dizziness; nausea, vomiting; dyspnea, chest pain; high fever. Direct contact may cause dermatitis. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 242; Patty's Industrial Hygiene and Toxicology vol. 2B, G. D. Clayton, F. E. Clayton, Eds. (Wiley-Interscience, New York, 1994) pp 1603-1613.
Use: Insecticide for termite control; pre-harvest defoliant; general herbicide. Antimicrobial preservative and fungicide for wood, wood products, starches, textiles, paints, adhesives, leather, pulp, paper, industrial waste systems, building materials. Surface disinfectant. |