Title: Mirex
CAS Registry Number: 2385-85-5
CAS Name: 1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene
Additional Names: perchloropentacyclo[5.2.1.02,6.03,9.05,8]decane; hexachloropentadiene dimer
Manufacturers' Codes: CG-1283; ENT-025719
Trademarks: Dechlorane (Occidental)
Molecular Formula: C10Cl12
Molecular Weight: 545.54
Percent Composition: C 22.02%, Cl 77.98%
Literature References: Prepn: Prins, Rec. Trav. Chim. 65, 455 (1946); Newcomer, McBee, J. Am. Chem. Soc. 71, 952 (1949); Gilbert, US 2702305 (1955 to Allied Chem.); Johnson, US 2724730 (1955 to Hooker Electrochem.). Structure: McBee et al., J. Am. Chem. Soc. 78, 1511 (1956). Degradation in the environment to Kepone and related compds: D. A. Carlson et al., Science 194, 939 (1976). Carcinogenicity study: B. M. Ullard et al., J. Natl. Cancer Inst. 58, 133 (1977). Toxicity data: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969). Reviews: Ungnade, McBee, Chem. Rev. 58, 249-320 (1958); Alley, J. Environ. Qual. 2, 52-61 (1973); E. M. Waters et al., Environ. Res. 14, 212-222 (1977); K. Kaiser, Environ. Sci. Technol. 12, 520-528 (1978). Review of toxicology and human exposure: Toxicological Profile for Mirex and Chlordecone (PB95-264354, 1995) 362 pp.
Properties: Snow-white odorless crystals from benzene, dec 485°. Supports combustion. Practically insol in water. Soly at room temp: dioxane 15.3%; xylene 14.3%; benzene 12.2%; carbon tetrachloride 7.2%; methyl ethyl ketone 5.6%. Practically noncorrosive to metals. LD50 orally in female rats (corn oil suspension): 600 mg/kg (Gaines).
Toxicity data: LD50 orally in female rats (corn oil suspension): 600 mg/kg (Gaines)
CAUTION: This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-175.
Use: Formerly as fire retardant for plastics, rubber, paint, paper, electrical goods; insecticide for fire ants. |