Title: Medifoxamine
CAS Registry Number: 32359-34-5
CAS Name: N,N-Dimethyl-2,2-diphenoxyethanamine
Additional Names: (dimethylamino)acetaldehyde diphenyl acetal; N,N¢-dimethyl-2,2-diphenoxyethylamine
Molecular Formula: C16H19NO2
Molecular Weight: 257.33
Percent Composition: C 74.68%, H 7.44%, N 5.44%, O 12.43%
Literature References: Prepn: FR M5498 (1967 to Gerda), C.A. 72, 12358x (1970); M. A. Brunet et al., Bull. Soc. Chim. Fr. 6, 2000 (1967). Pharmacology and toxicity: A. Vagne et al., Therapie 26, 553 (1971). Clinical pharmacology: M. A. Randhawa et al., Hum. Psychopharmacol. 3, 195 (1988). Comparative clinical trial with clomipramine, q.v., in depression: H. Scharbach et al., Psychol. Med. 18, 1485 (1986).
Derivative Type: Fumarate
CAS Registry Number: 16604-45-8
Manufacturers' Codes: LG-152
Trademarks: Clédial (Anphar-Rolland); Gerdaxyl (Gerda)
Molecular Formula: C16H19NO2.C4H4O4
Molecular Weight: 373.40
Percent Composition: C 64.33%, H 6.21%, N 3.75%, O 25.71%
Properties: Crystals from 95% ethanol, mp 128.5°. LD50 orally in rats: 750 mg/kg (Vagne).
Melting point: mp 128.5°
Toxicity data: LD50 orally in rats: 750 mg/kg (Vagne)
Therap-Cat: Antidepressant.
Keywords: Antidepressant. |