Title: Bunamiodyl Sodium
CAS Registry Number: 1923-76-8
CAS Name: 2-[[2,4,6-Triiodo-3-[(1-oxobutyl)amino]phenyl]methylene]butanoic acid monosodium salt
Additional Names: 3-butyramido-a-ethyl-2,4,6-triiodocinnamic acid sodium salt; 3-(3-butyrylamino-2,4,6-triiodophenyl)-2-ethylacrylic acid sodium salt; a-ethyl-b-(2,4,6-triiodo-3-butyramidophenyl)acrylic acid sodium salt; a-(2,4,6-triiodo-3-butyrylaminobenzylidene)butyric acid sodium salt; sodium 3-butyramido-a-ethyl-2,4,6-triiodocinnamate; buniodyl
Trademarks: Bunaiod; Orabilex (Fougera); Orabilix (Guerbet)
Molecular Formula: C15H15I3NNaO3
Molecular Weight: 660.99
Percent Composition: C 27.26%, H 2.29%, I 57.60%, N 2.12%, Na 3.48%, O 7.26%
Literature References: Prepn: Cassebaum, Dierbach, Pharmazie 16, 389 (1961). Acute toxicity: J. O. Hoppe et al., J. Med. Chem. 13, 997 (1970).
Properties: Crystals from water (free acid, mp 105-120°). Slightly sol in water. LD50 in mice: 418 mg/kg i.v.; 2.78 g/kg orally (Hoppe).
Melting point: free acid, mp 105-120°
Toxicity data: LD50 in mice: 418 mg/kg i.v.; 2.78 g/kg orally (Hoppe)
Therap-Cat: Diagnostic aid (radiopaque medium).
Keywords: Diagnostic Aid (Radiopaque Medium). |