epsilon-Acetamidocaproic Acid
Title: e-Acetamidocaproic Acid
CAS Registry Number: 57-08-9
CAS Name: 6-(Acetylamino)hexanoic acid
Additional Names: 6-acetamidohexanoic acid; acetaminocaproic acid; acexamic acid; N-acetyl-6-aminohexanoic acid
Molecular Formula: C8H15NO3
Molecular Weight: 173.21
Percent Composition: C 55.47%, H 8.73%, N 8.09%, O 27.71%
Line Formula: CH3CONH(CH2)5COOH
Literature References: Prepn: Offe, Z. Naturforsch. 2b, 182 (1947); FR M2332 (1964 to Rowa), C.A. 61, 577b (1964). Anti-inflammatory activity of salts: O. Guillard et al., Pharmacology 34, 296 (1987). Clinical comparison with ranitidine in gastroduodenal ulcer: M. J. Varas Lorenzo, Curr. Ther. Res. 39, 19 (1986).
Properties: Crystals from acetone, mp 104-105.5° (FR M2332), mp 112° (Offe).
Melting point: mp 104-105.5° (FR M2332); mp 112° (Offe)
 
Derivative Type: Sodium salt
CAS Registry Number: 7234-48-2
Trademarks: Plastenan (Isopharm)
Molecular Formula: C8H14NNaO3
Molecular Weight: 195.19
Percent Composition: C 49.23%, H 7.23%, N 7.18%, Na 11.78%, O 24.59%
 
Derivative Type: Zinc salt
CAS Registry Number: 70020-71-2
Additional Names: Zinc acexamate
Trademarks: Copinal (Vinas)
Molecular Formula: C16H28N2O6Zn
Molecular Weight: 409.81
Percent Composition: C 46.89%, H 6.89%, N 6.84%, O 23.42%, Zn 15.96%
 
Therap-Cat: Anti-inflammatory; zinc salt as antiulcerative.
Keywords: Anti-inflammatory (Nonsteroidal).

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