Title: Sparassol
CAS Registry Number: 520-43-4
CAS Name: 2-Hydroxy-4-methoxy-6-methylbenzoic acid methyl ester
Additional Names: 4-methoxy-2,6-cresotic acid methyl ester; everninic acid methyl ester; orsellinic acid methyl ester 4-methyl ether
Molecular Formula: C10H12O4
Molecular Weight: 196.20
Percent Composition: C 61.22%, H 6.16%, O 32.62%
Literature References: Antibiotic substance produced by the fungus Sparassis ramosa: Falck, Ber. 56, 2555 (1923). Also obtained in methanol extracts of the lichen Evernia prunasti: Stenhouse, Ann. 68, 55 (1848); Späth, Jeschki, Ber. 57, 471 (1924). Structure: Fischer, Hoesch, Ann. 391, 347 (1912); Wedekind, Fleischer, Ber. 56, 2556 (1923). Synthesis: G. Nicollier et al., Helv. Chim. Acta 61, 2899 (1978).
Properties: Prisms from water, mp 67-68°. Slightly sol in hot water; freely sol in acetone, ether, chloroform; moderately sol in methanol, ethanol, petr ether. Alkaline hydrolysis yields free everninic acid, mp 170°.
Melting point: mp 67-68°; mp 170° |