Title: Pyridofylline
CAS Registry Number: 53403-97-7
CAS Name: 3,7-Dihydro-1,3-dimethyl-7-[2-(sulfooxy)ethyl]-1H-purine-2,6-dione compd with 5-hydroxy-6-methyl-3,4-pyridinedimethanol (1:1)
Additional Names: 7-(2-hydroxyethyl)theophylline hydrogen sulfate compound with pyridoxol; b-[1,3-dimethyl-2,6(1H,3H)-purinedion-7-yl]ethyl sulfate of 5-hydroxy-6-methyl-3,4-pyridinedimethanol; pyridoxol compd with 7-(2-hydroxyethyl)theophylline hydrogen sulfate; theophyllineethyl sulfate of pyridoxine
Trademarks: Atherophylline
Molecular Formula: C17H23N5O9S
Molecular Weight: 473.46
Percent Composition: C 43.13%, H 4.90%, N 14.79%, O 30.41%, S 6.77%
Literature References: Prepn and therapeutic properties: A. Debarge, FR M828 (1961), C.A. 58, 9098g (1963).
Properties: Crystals from abs alcohol, mp 144-146°. LD50 in mice (g/kg): 1 i.v.; 1.6 orally (Debarge).
Melting point: mp 144-146°
Toxicity data: LD50 in mice (g/kg): 1 i.v.; 1.6 orally (Debarge)
Therap-Cat: Respiratory stimulant; vasodilator (coronary).
Keywords: Respiratory Stimulant; Vasodilator (Coronary).
Status: This monograph has been retired and is no longer subject to revision or update. |