Title: Pipobroman
CAS Registry Number: 54-91-1
CAS Name: 1,4-Bis-(3-bromo-1-oxopropyl)piperazine
Additional Names: 1,4-bis-(3-bromopropionyl)piperazine
Manufacturers' Codes: A-8103; NSC-25154
Trademarks: Amedel (Dainippon); Vercyte (Abbott)
Molecular Formula: C10H16Br2N2O2
Molecular Weight: 356.05
Percent Composition: C 33.73%, H 4.53%, Br 44.88%, N 7.87%, O 8.99%
Literature References: Prepn: Horrom, Carbon, DE 1138781 (1962 to Abbott), C.A. 58, 7955c (1963); Groszkowski, Rocz. Chem. 38, 229 (1964), C.A. 60, 14506a (1964). Structure-cytostatic effect studies: Groszkowski et al., J. Med. Chem. 11, 621 (1968); Oteleanu, Retezeanu, Farmacia (Bucharest) 16, 279 (1968), C.A. 69, 33591w (1968).
Properties: Crystals, mp 106-107°.
Melting point: mp 106-107°
Therap-Cat: Antineoplastic.
Keywords: Antineoplastic; Alkylating Agents. |