Title: Penthienate Bromide
CAS Registry Number: 60-44-6
CAS Name: 2-[(Cyclopentylhydroxy-2-thienylacetyl)oxy]-N,N-diethyl-N-methylethanaminium bromide
Additional Names: diethyl(2-hydroxyethyl)methylammonium bromide a-cyclopentyl-2-thiopheneglycolate; diethyl-2-[1-hydroxy-1-cyclopentyl-1-(2-thienyl)acetoxy]ethylmethylammonium bromide; 2-diethylaminoethyl 2-cyclopentyl-2-(2-thienyl)hydroxyacetate methobromide; 2-diethylaminoethyl-a-cyclopentyl-2-thiopheneglycolate methobromide
Manufacturers' Codes: Win-4369
Trademarks: Monodral bromide (Winthrop)
Molecular Formula: C18H30BrNO3S
Molecular Weight: 420.40
Percent Composition: C 51.43%, H 7.19%, Br 19.01%, N 3.33%, O 11.42%, S 7.63%
Literature References: Anticholinergic. Prepn: Blicke, Tsao, J. Am. Chem. Soc. 66, 1645 (1944); Blicke, US 2541634 (1951).
Properties: Pale yellow crystals, mp 124.6°. uv max: 238 nm (A1%1cm 189). One gram dissolves in 5 ml water. Freely sol in alc, chloroform. Slightly sol in acetone. Insol in ether. pH of a 1% aq soln 5.5 to 7.0.
Melting point: mp 124.6°
Absorption maximum: uv max: 238 nm (A1%1cm 189)
Therap-Cat: Antispasmodic.
Keywords: Antimuscarinic; Antispasmodic.
Status: This monograph has been retired and is no longer subject to revision or update. |