Nitroxynil
Title: Nitroxynil
CAS Registry Number: 1689-89-0
CAS Name: 4-Hydroxy-3-iodo-5-nitrobenzonitrile
Trademarks: Dovenix (Specia)
Molecular Formula: C7H3IN2O3
Molecular Weight: 290.01
Percent Composition: C 28.99%, H 1.04%, I 43.76%, N 9.66%, O 16.55%
Literature References: Prepn: NL 6516359 corresp to Collins et al., US 3331738 (1966, 1967 both to May & Baker).
Properties: Yellow crystals from benzene, mp 137-138°. Sparingly sol in water; moderately sol in most organic solvents.
Melting point: mp 137-138°
 
Derivative Type: D-N-Methylglucamine salt
CAS Registry Number: 36508-79-9
Additional Names: Nitroxynil meglumine; 4-hydroxy-3-iodo-5-nitrobenzonitrile compd with D-1-deoxy-1-(methylamino)glucitol (1:1)
Molecular Formula: C14H20IN3O8
Molecular Weight: 485.23
Percent Composition: C 34.65%, H 4.15%, I 26.15%, N 8.66%, O 26.38%
Properties: Solid, mp 85-90°.
Melting point: mp 85-90°
 
Derivative Type: N-Ethylglucamine
CAS Registry Number: 27917-82-4
Additional Names: Nitroxynil eglumine; 4-hydroxy-3-iodo-5-nitrobenzonitrile compd with 1-deoxy-1-(ethylamino)glucitol (1:1)
Trademarks: Trodax
Molecular Formula: C15H22IN3O8
Molecular Weight: 499.25
Percent Composition: C 36.09%, H 4.44%, I 25.42%, N 8.42%, O 25.64%
Properties: Readily sol in water with a yellow, odorless and substantially neutral soln. Aq soln is very stable but contamination with calcium and certain other salts can result in pptn of an insol salt of nitroxynil.
 
Therap-Cat-Vet: Anthelmintic (fasciolicide).

Others monographs:
Thorium Tetracyanoplatinate(II)Lita®Py-PhePyrene
Terodiline9-Carbazoleacetic AcidBarium BenzenesulfonateTyloxapol
MelanotanPhenoxazineUricaseMeclofenamic Acid
NiobiumDioscorineTeriparatide AcetateBerkelium
©2016 DrugLead US FDA&EMEA