Title: Nipecotic Acid
CAS Registry Number: 498-95-3
CAS Name: 3-Piperidinecarboxylic acid
Additional Names: hexahydronicotinic acid
Molecular Formula: C6H11NO2
Molecular Weight: 129.16
Percent Composition: C 55.79%, H 8.58%, N 10.84%, O 24.77%
Literature References: Prepd by hydrogenation of nicotinic acid with platinum oxide catalyst: McElvain, Adams, J. Am. Chem. Soc. 45, 2738 (1923); with rhodium on alumina catalyst: Freifelder, J. Org. Chem. 28, 1135 (1963); idem, US 3159639 (1964 to Abbott).
Properties: Crystals, mp 261° (dec). Freely sol in water. Practically insol in abs alcohol and ether.
Melting point: mp 261° (dec)
Derivative Type: Hydrochloride
Molecular Formula: C6H11NO2.HCl
Molecular Weight: 165.62
Percent Composition: C 43.51%, H 7.30%, N 8.46%, O 19.32%, Cl 21.41%
Properties: mp 240-242°. Very sol in water; slightly sol in alc (also reported as freely sol in alc); slightly sol in chloroform. Practically insol in ether, benzene, and acetone.
Melting point: mp 240-242°
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