Title: Nifuroxime
CAS Registry Number: 6236-05-1
CAS Name: 5-Nitro-2-furancarboxaldehyde oxime
Additional Names: anti-5-nitro-2-furaldoxime
Trademarks: Micofur (Norwich)
Molecular Formula: C5H4N2O4
Molecular Weight: 156.10
Percent Composition: C 38.47%, H 2.58%, N 17.95%, O 41.00%
Literature References: Prepd by treating 5-nitrofurfural with hydroxylamine in alcohol: Ikeda, C.A. 50, 10701 (1956). Claimed in Stillman et al., US 2319481 (1943 to Norwich Pharmacal).
Properties: Tasteless, pale yellow or greenish crystals from ethanol. Darkens on exposure to light. mp 156° (Ikeda); mp 163-164° (Stillman et al.). Soly at 25° in water: ~1 g/l, in methanol: 89.0 g/l, in 95% ethanol: 39.0 g/l.
Melting point: mp 156° (Ikeda); mp 163-164° (Stillman et al.)
Therap-Cat: Topical anti-infective; antiprotozoal (Trichomonas).
Keywords: Antiprotozoal (Trichomonas); Antiseptic/Disinfectant; Nitrofurans. |