Title: Monobenzone
CAS Registry Number: 103-16-2
CAS Name: 4-(Phenylmethoxy)phenol
Additional Names: p-(benzyloxy)phenol; hydroquinone monobenzyl ether; hydroquinone benzyl ether; p-hydroxyphenyl benzyl ether; benzyl hydroquinone; monobenzyl hydroquinone
Trademarks: Benoquin; Depigman (Hermal); Pigmex; Benzoquin; Agerite
Molecular Formula: C13H12O2
Molecular Weight: 200.23
Percent Composition: C 77.98%, H 6.04%, O 15.98%
Literature References: Prepd from hydroquinone and benzyl bromide in alcoholic KOH: Schiff, Pellizzari, Ann. 221, 370 (1883). Clinical evaluation: S. W. Becker, Jr., M. C. Spencer, J. Am. Med. Assoc. 180, 279 (1962). Toxicity study: A. Takahashi, E. A. Inglis, Int. J. Polymer Sci. Technol. 3, 93 (1976).
Properties: Lustrous leaflets from water, mp 122.5°. Practically insol in cold water. Soly in boiling water ~1.0 g/100 ml. Sol in alcohol, ether, benzene. LD50 i.p. in mice: >600 mg/kg (Takahashi).
Melting point: mp 122.5°
Toxicity data: LD50 i.p. in mice: >600 mg/kg (Takahashi)
Therap-Cat: Depigmentor.
Keywords: Depigmentor. |