Title: Meralluride
CAS Registry Number: 8069-64-5
CAS Name: [3-[[[(3-Carboxylato-1-oxopropyl)amino]carbonyl]amino]-2-methoxypropyl]hydroxymercurate(1-) sodium, mixture with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Additional Names: N-[[2-methoxy-3-[(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxopurin-7-yl)mercuri]propyl]carbamoyl]succinamic acid
Trademarks: Mercuhydrin; Mercuretin
Molecular Formula: C16H23HgN6NaO8
Molecular Weight: 650.97
Percent Composition: C 29.52%, H 3.56%, Hg 30.81%, N 12.91%, Na 3.53%, O 19.66%
Literature References: Structure: Pearson, Sigal, J. Org. Chem. 15, 1055 (1950). Toxicity data: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971).
Properties: White to slightly yellow powder, slowly dec on exposure to light. Saturated soln is acid to litmus. Slightly sol in water; sol in hot water, glacial acetic acid, and solns of alkali hydroxides. Almost insol in alc, chloroform, ether. LD50 s.c. in rats: 28±7 mg/kg (Goldenthal).
Toxicity data: LD50 s.c. in rats: 28±7 mg/kg (Goldenthal)
Therap-Cat: Diuretic.
Therap-Cat-Vet: Diuretic.
Keywords: Diuretic; Organomercurials. |