Title: Fenoxedil
CAS Registry Number: 54063-40-0
CAS Name: 2-(4-Butoxyphenoxy)-N-(2,5-diethoxyphenyl)-N-[2-(diethylamino)ethyl]acetamide
Additional Names: 2-(p-butoxyphenyl)-N-[2-(diethylamino)ethyl]-2¢,5¢-diethoxyacetanilide
Molecular Formula: C28H42N2O5
Molecular Weight: 486.64
Percent Composition: C 69.11%, H 8.70%, N 5.76%, O 16.44%
Literature References: Prepn: DE 1964712; Thuillier, Geffroy, US 3818021 (1970, 1974 both to CERPHA).
Derivative Type: Hydrochloride
CAS Registry Number: 27471-60-9
Trademarks: Suplexedil (Hatrol)
Molecular Formula: C28H42N2O5.HCl
Molecular Weight: 523.10
Percent Composition: C 64.29%, H 8.29%, N 5.36%, O 15.29%, Cl 6.78%
Properties: mp 140°. LD50 in mice (mg/kg): 750 orally, 17 i.v. (Thuillier, Geffroy).
Melting point: mp 140°
Toxicity data: LD50 in mice (mg/kg): 750 orally, 17 i.v. (Thuillier, Geffroy)
Therap-Cat: Vasodilator.
Keywords: Vasodilator (Cerebral); Vasodilator (Peripheral). |