Title: Delmadinone Acetate
CAS Registry Number: 13698-49-2
CAS Name: 17-(Acetyloxy)-6-chloropregna-1,4,6-triene-3,20-dione
Additional Names: 6-chloro-17-hydroxypregna-1,4,6-triene-3,20-dione acetate; 1,6-bisdehydro-6-chloro-17a-acetoxyprogesterone; D1-chlormadinone acetate
Manufacturers' Codes: RS-1301
Trademarks: Delminal (Rh>e-Mieux); Estrex (Syntex); Tardastrex (Gruntex); Tarden (Veterinaria); Zenadrex (Veterinaria)
Molecular Formula: C23H27ClO4
Molecular Weight: 402.91
Percent Composition: C 68.56%, H 6.75%, Cl 8.80%, O 15.88%
Literature References: Prepn: Ringold et al., J. Am. Chem. Soc. 81, 3485 (1959); GB 890315 (1962 to Upjohn), C.A. 57, 5996c (1962); 76, 14813y (1972); Campbell, Babcock, DE 1243682 (1967 to Upjohn), C.A. 67, 100343r (1967). Activity studies: Dorfman, Kincl, Steroids 1, 185 (1963); Weichert et al., Arzneim.-Forsch. 17, 1103 (1967); Gerber et al., J. Small Anim. Pract. 14, 151 (1973).
Properties: Crystals, mp 168-170°. [a]D -83° (chloroform). uv max (ethanol): 229, 258, 297 nm (log e 4.00, 4.00, 4.03).
Melting point: mp 168-170°
Optical Rotation: [a]D -83° (chloroform)
Absorption maximum: uv max (ethanol): 229, 258, 297 nm (log e 4.00, 4.00, 4.03)
Therap-Cat: Progestogen.
Therap-Cat-Vet: Progestogen.
Keywords: Progestogen. |