Title: Coumingine
CAS Registry Number: 26241-81-6
CAS Name: [2S-(2a,4aa,4bb,7E,8b,8aa,10ab)]-3-Hydroxy-3-methylbutanoic acid 7-[2-[2-(dimethylamino)ethoxy]-2-oxoethylidene]tetradecahydro-1,1,4a,8-tetramethyl-9-oxo-2-phenanthrenyl ester
Molecular Formula: C29H47NO6
Molecular Weight: 505.69
Percent Composition: C 68.88%, H 9.37%, N 2.77%, O 18.98%
Literature References: Cardiotonic principle from the bark of Erythrophleum couminga Baillon, Leguminosae. Isoln: Ruzicka et al., Helv. Chim. Acta 24, 63 (1941). Structure: Ruzicka et al., ibid. 1449.
Properties: Thin shiny needles from ether, mp 142°. [a]D20 -70°. Sol in methanol, ethanol, acetone, acetic acid, benzene, chloroform. Practically insol in water, hexane, ether.
Melting point: mp 142°
Optical Rotation: [a]D20 -70°
Derivative Type: Hydrochloride
Molecular Formula: C29H47NO6.HCl
Molecular Weight: 542.15
Percent Composition: C 64.25%, H 8.92%, N 2.58%, O 17.71%, Cl 6.54%
Properties: Crystals from ethanol + ether, mp 195°. Sol in ethanol, water.
Melting point: mp 195°
|