Title: Chloracizine
CAS Registry Number: 800-22-6
CAS Name: 2-Chloro-10-[3-(diethylamino)-1-oxopropyl]-10H-phenothiazine
Additional Names: 2-chloro-10-(N,N-diethyl-b-alanyl)phenothiazine; 10-(b-diethylaminopropionyl)-2-chlorophenothiazine; 2-chloro-10-(b-diethylaminopropionyl)phenothiazine; chloracysin; chlorocyzine; chlorocizin; khloratsizin
Manufacturers' Codes: G-020
Molecular Formula: C19H21ClN2OS
Molecular Weight: 360.90
Percent Composition: C 63.23%, H 5.86%, Cl 9.82%, N 7.76%, O 4.43%, S 8.88%
Literature References: Prepn: Horclois, Metivier, FR 1060715 (1954 to Rhône Poulenc); GB 740932 (1955); Zhuravlev, Gritsenko, Zh. Obshch. Khim. 26, 3385 (1956), C.A. 51, 9623h (1957). For other prepns in Russian journals see C.A. 55, 6484b, 9425a (1961).
Derivative Type: Hydrochloride
Molecular Formula: C19H21ClN2OS.HCl
Molecular Weight: 397.36
Percent Composition: C 57.43%, H 5.58%, Cl 17.84%, N 7.05%, O 4.03%, S 8.07%
Properties: Crystals from isopropanol, mp 168-169°. Sol in water.
Melting point: mp 168-169°
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary). |