Title: Broparoestrol
CAS Registry Number: 479-68-5
CAS Name: 1-(2-Bromo-1,2-diphenylethenyl)-4-ethylbenzene
Additional Names: 1-bromo-2-(p-ethylphenyl)-1,2-diphenylethylene; 1-bromo-2-(4-ethylphenyl)-1,2-diphenylethene; a-bromo-a,b-diphenyl-b-(p-ethylphenyl)ethylene; 1-(p-ethylphenyl)-1,2-diphenyl-2-bromoethylene; B.D.P.E.
Manufacturers' Codes: LN-107
Trademarks: Acnestrol (Dermik); Longestrol (Syntex)
Molecular Formula: C22H19Br
Molecular Weight: 363.29
Percent Composition: C 72.73%, H 5.27%, Br 21.99%
Literature References: Prepn: Dvolaitsky, Jacques, Bull. Soc. Chim. Biol. 40, 939 (1958).
Derivative Type: cis-trans Mixture
Properties: Crystals, mp 89°. (Isomer A, needles from ethanol, mp 112-113.5°; isomer B, mp 111.5-112°). The commercial medicinal product is the cis-trans mixture. Soluble in ether, benzene, chloroform; less sol in ethanol.
Melting point: mp 89°; Isomer A, needles from ethanol, mp 112-113.5°; isomer B, mp 111.5-112°
Therap-Cat: Estrogen. Used in dermatology.
Keywords: Estrogen; Nonsteroidal. |