Title: Azidocillin
CAS Registry Number: 17243-38-8
CAS Name: (2S,5R,6R)-6-[[(2R)-Azidophenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Additional Names: a-azidobenzylpenicillin; 6-[D-a-azidophenylacetamido]penicillanic acid
Manufacturers' Codes: SPC-97D; BRL-2351
Molecular Formula: C16H17N5O4S
Molecular Weight: 375.40
Percent Composition: C 51.19%, H 4.56%, N 18.66%, O 17.05%, S 8.54%
Literature References: Semi-synthetic antibiotic related to penicillin. Prepn: B. O. H. Sjöberg, B. A. Ekström, GB 940488; eidem, US 3293242 (1963, 1966 to Beecham); Ekström et al., Acta Chem. Scand. 19, 281 (1965). Pharmacology: Hanssen et al., Antimicrob. Agents Chemother. 1967, 568; Tunevall, Frisk, ibid. 573. Chemistry: Sjöberg et al., ibid. 560. Metabolic studies: Ramsey et al., Arzneim.-Forsch. 22, 1962 (1972).
Derivative Type: Sodium salt
CAS Registry Number: 35334-12-4
Trademarks: Globacillin (Astra); Longatren (Bayer); Syncillin (Bayer)
Molecular Formula: C16H16N5NaO4S
Molecular Weight: 397.38
Percent Composition: C 48.36%, H 4.06%, N 17.62%, Na 5.79%, O 16.10%, S 8.07%
Therap-Cat: Antibacterial.
Therap-Cat-Vet: Antimicrobial. (In mastitis, as feed supplement).
Keywords: Antibacterial (Antibiotics); ?Lactams; Penicillins. |