Title: Arsenamide
CAS Registry Number: 531-72-6
CAS Name: 2,2¢-[[[4-(Aminocarbonyl)phenyl]arsinidene]bis(thio)]bisacetic acid
Additional Names: [[(p-carbamoylphenyl)arsylene]dithio]diacetic acid; bis[carboxymethylmercapto](p-carbamylphenyl)-arsine; p-[bis(carboxymethylmercapto)arsino]benzamide; dithioglycolyl p-arsenobenzamide; 4-carbamylphenyl bis[carboxymethylthio]arsenite; thioarsenite; thiacetarsamide
Trademarks: Caparsolate (Abbott); Caparside
Molecular Formula: C11H12AsNO5S2
Molecular Weight: 377.27
Percent Composition: C 35.02%, H 3.21%, As 19.86%, N 3.71%, O 21.20%, S 17.00%
Literature References: Prepd by the condensation of p-arsenosobenzamide and thioglycolic acid: Gough, King J. Chem. Soc. 1930, 669; Maren, J. Am. Chem. Soc. 68, 1864 (1946).
Properties: White crystalline powder. Sparingly sol in cold water; appreciably sol in water above 90°. Sparingly sol in cold methanol, ethanol; very sol in these solvents when they are warm. Insol in warm isopropyl ether. pKa = 4. The disodium salt is stoichiometrically formed in aq soln at pH 7-8.
pKa: pKa = 4
Therap-Cat-Vet: Anthelmintic for heartworm infection in dogs, especially the adult worm. |