Title: Arsanilic Acid
CAS Registry Number: 98-50-0
CAS Name: (4-Aminophenyl)arsonic acid
Additional Names: p-aminobenzenearsonic acid; atoxylic acid
Manufacturers' Codes: AS-101
Molecular Formula: C6H8AsNO3
Molecular Weight: 217.05
Percent Composition: C 33.20%, H 3.72%, As 34.52%, N 6.45%, O 22.11%
Literature References: Prepd by heating aniline and arsenic acid: Lewis, Cheetham, Org. Synth. coll. vol. I (2nd ed., 1941) p 70; Hoffmann, Green, US 3763201 (1973); from p-nitroaniline: Bart, Ann. 429, 96 (1922); Gattermann-Wieland, Praxis des Organischen Chemikers (de Gruyter, Berlin, 40th ed., 1961) p 254. Toxicology in swine: Ledet et al., Clin. Toxicol. 6, 439 (1973). Toxicity study: E. I. Goldenthal, Toxicol. Appl. Pharmacol. 18, 185 (1971). Review of toxicology and human exposure: Toxicological Profile for Arsenic (PB2000-108021, 2000) 468 pp.
Properties: Needles from water or alcohol. Slightly sol in cold water, alcohol or acetic acid; sol in hot water, pentanol, in solns of alkali carbonates; moderately sol in concd mineral acids. Practically insol in acetone, benzene, chloroform, ether, and in moderately dil mineral acids. LD50 orally in male rats: >1000 mg/kg (Goldenthal).
Toxicity data: LD50 orally in male rats: >1000 mg/kg (Goldenthal)
Use: Manuf medicinal arsenicals.
Therap-Cat-Vet: Growth promotant; to improve feed efficiency. To control swine dysentery. |