Title: Alminoprofen
CAS Registry Number: 39718-89-3
CAS Name: a-Methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid
Additional Names: 2-(p-methylallylaminophenyl)propionic acid
Manufacturers' Codes: EB-382
Trademarks: Minalfene (Bouchara)
Molecular Formula: C13H17NO2
Molecular Weight: 219.28
Percent Composition: C 71.21%, H 7.81%, N 6.39%, O 14.59%
Literature References: Prepn: FR 2137211; E. Bouchera, US 3957850 (1971, 1976 both to Bouchera). Synthesis, pharmacology and toxicity data: B. Dumaitre et al., Eur. J. Med. Chem. 14, 207 (1979). Pharmacokinetic study: A. Premel-Cabic et al., Eur. J. Clin. Pharmacol. 18, 419 (1980).
Properties: Crystals from cyclohexane, mp 107°. LD50 orally in mice: 2400 mg/kg (Dumaitre).
Melting point: mp 107°
Toxicity data: LD50 orally in mice: 2400 mg/kg (Dumaitre)
Therap-Cat: Anti-inflammatory; analgesic.
Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives. |