Title: Acetylcholine Chloride
CAS Registry Number: 60-31-1
CAS Name: 2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride
Trademarks: Acecoline (Lematte et Boinot); Arterocoline; Miochol (Cooper); Ovisot
Molecular Formula: C7H16ClNO2
Molecular Weight: 181.66
Percent Composition: C 46.28%, H 8.88%, Cl 19.52%, N 7.71%, O 17.61%
Line Formula: (CH3)3N(Cl)CH2CH2OOCCH3
Literature References: Prepd from trimethylamine and b-chloroethyl acetate: Fourneau, Page, Bull. Soc. Chim. Fr. [4] 15, 544 (1914). Review of pharmacology: H. Molitor, J. Pharmacol. Exp. Ther. 58, 337 (1936).
Properties: Crystalline powder, very deliquescent, mp 149-152°. Hygroscopic. Very sol in cold water, alcohol; decomposed by hot water or alkalies. Practically insol in ether. Keep tightly closed. LD50 in mice, rats (mg/kg): 20, 22 i.v., 170, 250 s.c., 3000, 2500 i.p. (Molitor).
Melting point: mp 149-152°
Toxicity data: LD50 in mice, rats (mg/kg): 20, 22 i.v., 170, 250 s.c., 3000, 2500 i.p. (Molitor)
Therap-Cat: Cholinergic.
Keywords: Cholinergic. |