Title: Acetosulfone Sodium
CAS Registry Number: 128-12-1
CAS Name: N-[[5-Amino-2-[(4-aminophenyl)sulfonyl]phenyl]sulfonyl]acetamide monosodium salt
Additional Names: N-6-sulfanilylmetanilylacetamide N-sodium salt; N1-acetyl-6-(sulfanilylmetanilamido)sodium; sodium 2-N-acetylsulfamyl-4,4¢-diaminodiphenylsulfone; sodium 4,4¢-diaminodiphenylsulfone-2-N-acetylsulfonamide; sulfadiasulfone sodium; acetosulphone; Internal Antiseptic no. 307; I.A. 307
Trademarks: Promacetin (Parke-Davis)
Molecular Formula: C14H14N3NaO5S2
Molecular Weight: 391.40
Percent Composition: C 42.96%, H 3.61%, N 10.74%, Na 5.87%, O 20.44%, S 16.38%
Literature References: Prepn: Tullar, US 2358365 (1944 to Parke, Davis).
Properties: Crystals. Soly in water about 3%. mp ~285° (free sulfonamide).
Melting point: mp ~285° (free sulfonamide)
Therap-Cat: Antibacterial (leprostatic).
Keywords: Antibacterial (Synthetic); Sulfones; Antibacterial (Leprostatic).
Status: This monograph has been retired and is no longer subject to revision or update. |