Acemannan

Literature References: Long-chain, polydispersed, b-(1,4)-linked acetylated mannan obtained from the mucilage of Aloe barbadensis, Miller, Liliaceae (aloe vera). Isolation, purification, and characterization: B. H. McAnalley, WO 8700052; idem, US 4735935 (1987, 1988 both to Carrington Labs.). Structural study: S. Manna, B. H. McAnalley, Carbohydr. Res. 241, 317 (1993). Immunostimulant effect in vitro: D. Womble, J. H. Helderman, Int. J. Immunopharmacol. 10, 967 (1988). Inhibition of HIV-1 replication in vitro: J. B. Kahlon et al., Mol. Biother. 3, 127 (1991). Veterinary trial in feline-leukemia virus infection: M. A. Sheets et al., ibid. 41; in canine and feline spontaneous tumors: C. Harris et al., ibid. 207. Toxicological evaluation: R. W. Fogleman et al., Vet. Hum. Toxicol. 34, 201 (1992).