Title: 2,2,2-Trichloroethanol
CAS Registry Number: 115-20-8
Additional Names: Trichloroethyl alcohol
Molecular Formula: C2H3Cl3O
Molecular Weight: 149.40
Percent Composition: C 16.08%, H 2.02%, Cl 71.19%, O 10.71%
Line Formula: CCl3CH2OH
Literature References: Prepd by reduction of the corresponding ester, acid chloride, or acid with lithium aluminum hydride: Sroog et al., J. Am. Chem. Soc. 71, 1710 (1949). Manufacture by reduction of chloral hydrate with an amine borane: Chamberlain, Schechter, US 2898379 (1959 to Callery Chem.). Pharmacology: H. Molitor, H. Robinson, Curr. Res. Anesth. Analg. 17, 258 (1938).
Properties: Hygroscopic liquid, ethereal odor. At low temps it crystallizes in rhombic tablets. mp at 18°; bp 151-153°; d2020 1.55. Sol in about 12 parts water; miscible with alcohol or ether. pH of aq soln is 5-6, but on prolonged contact with water some free acid is formed. Keep well closed and protected from light.
Melting point: mp at 18°
Boiling point: bp 151-153°
Density: d2020 1.55
Therap-Cat: Sedative; hypnotic.
Keywords: Sedative/Hypnotic; Alcohols. |