Title: Trifenmorph
CAS Registry Number: 1420-06-0
CAS Name: 4-(Triphenylmethyl)morpholine
Additional Names: 4-tritylmorpholine
Manufacturers' Codes: WL-8008
Trademarks: Frescon (Shell)
Molecular Formula: C23H23NO
Molecular Weight: 329.43
Percent Composition: C 83.86%, H 7.04%, N 4.25%, O 4.86%
Literature References: Prepn: Adams et al., US 3577413 (1971 to Shell). Lab tests as molluscicide: Webbe, Sturrock, Ann. Trop. Med. Parasitol. 58, 234 (1964); C.A. 61, 15286g (1964). Field trials and toxicity: Boyce et al., Nature 210, 1140 (1966). Degradn: K. I. Beynon et al., Pestic. Sci. 3, 689 (1972). Neurophysiological action: R. B. Morton, D. R. Gardner, Experientia 32, 611 (1976).
Properties: Crystalline solid, mp 174-176°, resolidifies and melts again at 185-187°. Vapor pressure at 20°: 1.4 ´ 10-7 mm Hg. Soly in water at 20°: 0.02 mg/l. Soly at 20° (g/l): carbon tetrachloride 300; chloroform 450; tetrachloroethylene 255. Stable to heat and alkali but hydrolyzed by mild acidic conditions. LD50 orally in rats: 1200-2000 mg/kg (Boyce).
Melting point: mp 174-176°, resolidifies and melts again at 185-187°
Toxicity data: LD50 orally in rats: 1200-2000 mg/kg (Boyce)
Use: As molluscicide (against snails carrying bilharzia flukes).
Status: This monograph has been retired and is no longer subject to revision or update. |