Title: Thiazesim
CAS Registry Number: 5845-26-1
CAS Name: 5-[2-(Dimethylamino)ethyl]-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one
Additional Names: thiazenone; tiazesim
Molecular Formula: C19H22N2OS
Molecular Weight: 326.46
Percent Composition: C 69.90%, H 6.79%, N 8.58%, O 4.90%, S 9.82%
Literature References: Prepn of the hydrochloride: Krapcho et al., J. Med. Chem. 6(5), 544 (1963); Krapcho, US 3075967 (1963 to Olin Mathieson). Metabolism: J. Dreyfuss et al., J. Pharm. Sci. 57, 1497, 1505 (1968).
Derivative Type: Hydrochloride
CAS Registry Number: 3122-01-8
Manufacturers' Codes: SQ-10496
Trademarks: Altinil (BMS)
Molecular Formula: C19H22N2OS.HCl
Molecular Weight: 362.92
Percent Composition: C 62.88%, H 6.39%, N 7.72%, O 4.41%, S 8.84%, Cl 9.77%
Properties: Crystals from acetonitrile, mp 222-224°.
Melting point: mp 222-224°
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Bicyclics. |