Title: Tevenel® (Midy Labs)
CAS Registry Number: 4302-95-8
CAS Name: N-[(1R,2R)-2-[4-(Aminosulfonyl)phenyl]-2-hydroxy-1-(hydroxymethyl)ethyl]-2,2-dichloroacetamide
Additional Names: D-threo-(-)-2,2-dichloro-N-[b-hydroxy-a-(hydroxymethyl)-p-sulfamoylphenethyl]acetamide; D-threo-1-(p-sulfamoylphenyl)-2-(2¢,2¢-dichloroacetamido)-1,3-propanediol
Trademarks: AMP-3; D-AMP-3
Molecular Formula: C11H14Cl2N2O5S
Molecular Weight: 357.21
Percent Composition: C 36.99%, H 3.95%, Cl 19.85%, N 7.84%, O 22.39%, S 8.98%
Literature References: Sulfamoyl analog of chloramphenicol. Prepn: Gregory, US 2680135 (1954 to Du Pont). Toxicology: R. M. Jiji et al., Arch. Int. Med. 111, 70 (1963).
Properties: Crystals from acetonitrile, mp 155-158°. Sol in ethanol, propylene glycol. Slightly sol in water, dil aq solns of sodium bicarbonate, acetic acid. Aq solns are neutral.
Melting point: mp 155-158°
Therap-Cat: Anti-infective.
Status: This monograph has been retired and is no longer subject to revision or update. |