Title: TEMED
CAS Registry Number: 110-18-9
CAS Name: N,N,N¢,N¢-Tetramethyl-1,2-ethanediamine
Additional Names: TMEDA
Molecular Formula: C6H16N2
Molecular Weight: 116.20
Percent Composition: C 62.02%, H 13.88%, N 24.11%
Literature References: Prepn: M. Freund, H. Michaels, Ber. 30, 1374 (1897); W. Hanhart, C. K. Ingold, J. Chem. Soc. 1927, 997. Base strength: L. Spialter, R. W. Moshier, J. Am. Chem. Soc. 79, 5955 (1957). Effect on kinetics of gel polymerization: Y. Pegon, C. Quincy, J. Chromatogr. 100, 11 (1974); on gel pore size: H. Tamagawa et al., Polymer 41, 7201 (2000). Use as initiatior in electrophoresis: B. J. Bassam, S. Bentley, BioTechniques 19, 568 (1995); as chelator in biological redox systems: H. C. Chang, J. A. Bumpus, Proc. Natl. Sci. Counc. ROC(B) 25, 26 (2001); as solvent in RPLC: L. Palego et al., Prog. Neuro-Psychopharmacol. Biol. Psychiatry 25, 519 (2001); in capillary isoelectric focusing: D. Mohan, C. S. Lee, J. Chromatogr. A 979, 271 (2002).
Properties: Basic liquid. fp -55.1°. bp724 119.4-119.5°. nD18 1.4196. pKa1 5.85; pKa2 8.97.
Boiling point: bp724 119.4-119.5°
pKa: pKa1 5.85; pKa2 8.97
Index of refraction: nD18 1.4196
Use: Polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent. |