Pyrolan
Title: Pyrolan
CAS Registry Number: 87-47-8
CAS Name: Dimethylcarbamic acid 3-methyl-1-phenyl-1H-pyrazol-5-yl ester
Additional Names: 1-phenyl-3-methyl-5-pyrazolyl dimethylcarbamate; 3-methyl-1-phenyl-5-pyrazolyl dimethylcarbamate
Manufacturers' Codes: ENT-17588; G-22008
Molecular Formula: C13H15N3O2
Molecular Weight: 245.28
Percent Composition: C 63.66%, H 6.16%, N 17.13%, O 13.05%
Literature References: Prepn from 1-phenyl-3-methyl-5-pyrazolone and dimethylcarbamoyl chloride: CH 279553 (1952 to Geigy); GB 681376. Anticholinesterase activity: Pulver, Domenjoz, Experientia 7, 306 (1951); Ferguson, Alexander, J. Agric. Food Chem. 1, 888 (1953); Müller, Spindler, Experientia 10, 91 (1954). Toxicity study: E. W. Schafer, Toxicol. Appl. Pharmacol. 21, 315 (1972).
Properties: Crystals, mp 50°. bp0.2 160-162°. Possesses water and lipid solubility. LD50 orally in rats: 62 mg/kg (Schafer).
Melting point: mp 50°
Boiling point: bp0.2 160-162°
Toxicity data: LD50 orally in rats: 62 mg/kg (Schafer)
CAUTION: Cholinesterase inhibitor.
Use: Insecticide.

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