Title: Oxyphenisatin Acetate
CAS Registry Number: 115-33-3
CAS Name: 3,3-Bis[4-(acetyloxy)phenyl]-1,3-dihydro-2H-indol-2-one
Additional Names: 3,3-bis(p-acetoxyphenyl)oxindole; acetphenolisatin; endophenolphthalein; diacetyldiphenolisatin; diacetyldihydroxydiphenylisatin; diacetylhydroxyphenylisatin; diacetoxydiphenylisatin; di(acetoxyphenyl)oxindole; diphesatin; diacetyldioxyphenylisatin
Trademarks: Isacen; Isocrin (Warner-Chilcott); Isaphen; Laxo-Isatin; Promassolax; Sanapert; Bydolax; Cirotyl (Parke-Davis); Lisagal; Contax; Prulet (Mission Pharmacal); Purgaceen; Bisatin
Molecular Formula: C24H19NO5
Molecular Weight: 401.41
Percent Composition: C 71.81%, H 4.77%, N 3.49%, O 19.93%
Literature References: Prepd from isatin by treatment with phenol followed by acetylation in the presence of H2SO4 at temps below 100°: Baeyer, Lazarus, Ber. 18, 2641 (1885); Hoffmann-La Roche, CH 100806; DE 406210 (1923); US 1624675 (1927); DE 482435 (1929); Mizuno, Turuga, JP 129200 (1939).
Properties: Tasteless crystals, mp 242°. Practically insol in water, ether, dilute HCl. Slightly sol in alcohol.
Melting point: mp 242°
Therap-Cat: Cathartic.
Keywords: Laxative/Cathartic. |