Title: Octenidine
CAS Registry Number: 71251-02-0
CAS Name: N,N¢-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis[1-octanamine]
Additional Names: 1,10-bis-[4-(octylamino)-1-pyridinium]decane
Manufacturers' Codes: Win-41464
Molecular Formula: C36H62N4
Molecular Weight: 550.90
Percent Composition: C 78.49%, H 11.34%, N 10.17%
Literature References: Prepn: D. M. Bailey, BE 851807; idem, US 4206215 (1977, 1980 both to Sterling); D. M. Bailey et al., J. Med. Chem. 27, 1457 (1984). Structure-activity study: A. M. Slee et al., Antimicrob. Agents Chemother. 23, 531 (1983). Antiplaque activity: A. M. Slee, J. R. O'Connor, ibid. 379; microbiocidal activity: D. M. Sedlock, D. M. Bailey, ibid. 28, 786 (1985). Antimycotic effects: M. A. Ghannoum et al., J. Antimicrob. Chemother. 25, 237 (1990). Clinical evaluation as topical disinfectant: B. Christiansen, Z. Bakteriol. Mikrobiol. Hyg. 186, 368 (1988). Clinical trials in prevention of plaque and gingivitis: M. R. Patters et al., J. Periodontal Res. 21, 154 (1986); B. B. Beiswanger et al., J. Dent. Res. 69, 454 (1990).
Derivative Type: Dihydrochloride
CAS Registry Number: 70775-75-6
Manufacturers' Codes: Win-41464-2
Trademarks: Neo Kodan (Schîke & Mayr); Octeniderm (Sterling); Octenisept (Schîke & Mayr)
Molecular Formula: C36H62N2.2HCl
Molecular Weight: 595.81
Percent Composition: C 72.57%, H 10.83%, N 4.70%, Cl 11.90%
Properties: Solid from ether, mp 215-217°.
Melting point: mp 215-217°
Derivative Type: Disaccharin
CAS Registry Number: 86767-75-1
Manufacturers' Codes: Win-41464-6
Molecular Formula: C36H62N2.2C7H5NO3S
Molecular Weight: 889.26
Percent Composition: C 67.53%, H 8.16%, N 6.30%, O 10.80%, S 7.21%
Therap-Cat: Antiseptic (topical).
Keywords: Antiseptic/Disinfectant. |