Title: Isoxaben
CAS Registry Number: 82558-50-7
CAS Name: N-[3-(1-Ethyl-1-methylpropyl)-5-isoxazolyl]-2,6-dimethoxybenzamide
Additional Names: benzamizole
Manufacturers' Codes: EL-107; NA-8318
Trademarks: Flexidor (Dow AgroSci.); Gallery (Dow AgroSci.)
Molecular Formula: C18H24N2O4
Molecular Weight: 332.39
Percent Composition: C 65.04%, H 7.28%, N 8.43%, O 19.25%
Literature References: Selective, pre-emergent herbicide for broadleaf weeds and annual grasses. Prepn: K. W. Burow, GB 2084140; see also: idem, US 4636243 (1982, 1987 both to Lilly). Physical properties and herbicidal activity: F. Huggenberger et al., Proc. Br. Crop Prot. Conf. - Weeds 1982, 47. Mobility and degradation in soil: F. Huggenberger, P. J. Ryan, ibid. 1985, 947. Effect on cellular growth and metabolism: A. Lefebvre et al., Weed Res. 27, 125 (1987). Field trials: F. Huggenberger, F. Gueguen, Crop Prot. 6, 75 (1987); F. O. Colbert, D. H. Ford, Proc. West. Soc. Weed Sci. 40, 155 (1987).
Properties: White crystalline solid, mp 176-179°. Soly at 25° (mg/ml): methanol 50-100; ethyl acetate 50-100; acetonitrile 30-50; toluene 4-5; hexane 0.07-0.08; water 0.001-0.002. Vapor pressure at 30°: <3.9 ´ 10-7 mm Hg. LD50 in mice, rats (mg/kg): >10000 orally both species; LC50 in rats by inhalation: >1.99 mg/l (Huggenberger, 1982).
Melting point: mp 176-179°
Toxicity data: LD50 in mice, rats (mg/kg): >10000 orally both species; LC50 in rats by inhalation: >1.99 mg/l (Huggenberger, 1982)
Use: Herbicide. |