Title: Fagarine
CAS Registry Number: 524-15-2
CAS Name: 4,8-Dimethoxyfuro[2,3-b]quinoline
Additional Names: g-fagarine; 8-methoxydictamnine
Molecular Formula: C13H11NO3
Molecular Weight: 229.23
Percent Composition: C 68.11%, H 4.84%, N 6.11%, O 20.94%
Literature References: Antiarrhythmic principle in Fagara coco (Gill.) Engl., Rutaceae. Isoln: Deulofeu et al., J. Am. Chem. Soc. 64, 2326 (1942); Briggs, Cambi, Tetrahedron 2, 256 (1958). Structure: Berinzaghi et al., J. Org. Chem. 10, 181 (1945). Synthesis: Grundon, McCorkindale, Chem. Ind. (London) 1956, 1091.
Properties: Prisms from alcohol, mp 142°. uv max: 238, 332, 370 nm (log e 4.76, 3.88, 3.89). Sol in chloroform, benzene, ether; slightly sol in water, petr ether.
Melting point: mp 142°
Absorption maximum: uv max: 238, 332, 370 nm (log e 4.76, 3.88, 3.89)
Derivative Type: Hydrochloride
Molecular Formula: C13H12ClNO3
Molecular Weight: 265.69
Percent Composition: C 58.77%, H 4.55%, Cl 13.34%, N 5.27%, O 18.07%
Properties: Needles from chloroform + ether, mp 158-159°.
Melting point: mp 158-159°
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