Title: Dimoxyline
CAS Registry Number: 147-27-3
CAS Name: 1-(4-Ethoxy-3-methoxybenzyl)-6,7-dimethoxy-3-methylisoquinoline
Additional Names: 6,7-dimethoxy-3-methyl-1-(3¢-methoxy-4¢-ethoxybenzyl)isoquinoline; 6,7-dimethoxy-1-(4¢-ethoxy-3¢-methoxybenzyl)-3-methylisoquinoline; dioxyline
Trademarks: Paveril (Lilly)
Molecular Formula: C22H25NO4
Molecular Weight: 367.44
Percent Composition: C 71.91%, H 6.86%, N 3.81%, O 17.42%
Literature References: Prepn: Shepard, US 2728769 (1955 to Lilly).
Properties: Crystals from dil ethanol, mp 124-125°.
Melting point: mp 124-125°
Derivative Type: Hydrochloride
Molecular Formula: C22H25NO4.HCl
Molecular Weight: 403.90
Percent Composition: C 65.42%, H 6.49%, N 3.47%, O 15.84%, Cl 8.78%
Properties: Crystals, dec 196-208°.
Derivative Type: Phosphate
CAS Registry Number: 5667-46-9
Molecular Formula: C22H25NO4.H3PO4
Molecular Weight: 465.43
Percent Composition: C 56.77%, H 6.06%, N 3.01%, O 27.50%, P 6.65%
Properties: Crystals, dec 197-199°. More sol than the hydrochloride.
Therap-Cat: Vasodilator.
Status: This monograph has been retired and is no longer subject to revision or update. |