Title: Dihydrotachysterol
CAS Registry Number: 67-96-9
CAS Name: (3b,5E,7E,10a,22E)-9,10-Secoergosta-5,7,22-trien-3-ol
Additional Names: dichystrolum; anti-tetany substance 10; AT 10
Trademarks: Antitanil; Calcamine (Wander); Dygratyl (Ferrosan); Dihydral (Duphar); Hytakerol (Winthrop); Parterol; Tachyrol (Duphar)
Molecular Formula: C28H46O
Molecular Weight: 398.66
Percent Composition: C 84.36%, H 11.63%, O 4.01%
Literature References: Prepn by reduction of tachysterol: Windaus et al., Ann. 499, 198 (1932); v. Werder, US 2228491 (1941 to Winthrop), cf. Z. Physiol. Chem. 260, 119 (1939). Activity similar to parathyroid extract.
Properties: Needles from 90% methanol, mp 125-127°. [a]D22 +97.5° (chloroform). uv max: 242, 251, 261 nm (E1%1cm 870, 1010, 650). Insol in water. Easily sol in organic solvents.
Melting point: mp 125-127°
Optical Rotation: [a]D22 +97.5° (chloroform)
Absorption maximum: uv max: 242, 251, 261 nm (E1%1cm 870, 1010, 650)
Therap-Cat: Calcium regulator.
Keywords: Calcium Regulator. |