Title: Deoxydihydrostreptomycin
CAS Registry Number: 26086-49-7
CAS Name: O-2-Deoxy-2-(methylamino)-a-L-glucopyranosyl-(1®2)-O-3,5-dideoxy-3-(hydroxymethyl)-a-L-arabinofuranosyl-(1®4)-N,N¢-bis(aminoiminomethyl)-D-streptamine
Additional Names: dihydrodeoxystreptomycin
Trademarks: Desoxymycin (Kaken); Mervastrept
Molecular Formula: C21H41N7O11
Molecular Weight: 567.59
Percent Composition: C 44.44%, H 7.28%, N 17.27%, O 31.01%
Literature References: Reduction product of streptomycin. Prepn and structure: Ikeda, C.A. 50, 13765g (1956); Yabuta et al., US 2837510 (1958); Gailliot, Baget, FR 1198042 (1959 to Rhône-Poulenc). TLC separation: H. Heding, Acta Chem. Scand. 24, 3086 (1970). Comparative antibacterial activity of streptomycin analogs: H. Heding, O. Lützen, J. Antibiot. 25, 287 (1972).
Properties: Needles, dec 190-195°. [a]D20 -102.5° (water).
Optical Rotation: [a]D20 -102.5° (water)
Derivative Type: Sulfate
Properties: [a]D20 -78° (c = 2).
Optical Rotation: [a]D20 -78° (c = 2)
Therap-Cat: Antibacterial (tuberculostatic). |