Title: Demegestone
CAS Registry Number: 10116-22-0
CAS Name: 17-Methyl-19-norpregna-4,9-diene-3,20-dione
Additional Names: 17a-methyl-19-nor-D4,9-pregnadiene-3,20-dione; 17a-methyl-D9-19-norprogesterone
Manufacturers' Codes: R-2453
Trademarks: Lutionex (Roussel Diamant)
Molecular Formula: C21H28O2
Molecular Weight: 312.45
Percent Composition: C 80.72%, H 9.03%, O 10.24%
Literature References: Prepn: NL 6517141; R. Joly et al., US 3547959 (1966, 1970 both to Roussel-UCLAF); L. Velluz et al., Tetrahedron Suppl. 8, part II, 495 (1966); R. Joly et al., Bull. Soc. Chim. Fr. 1973, 2694.
Properties: Crystals from ether, mp 106°. [a]D -275° (c = 0.5 in ethanol). uv max (ethanol): 214, 302 nm (e 6350, 21000).
Melting point: mp 106°
Optical Rotation: [a]D -275° (c = 0.5 in ethanol)
Absorption maximum: uv max (ethanol): 214, 302 nm (e 6350, 21000)
Therap-Cat: Progestogen.
Keywords: Progestogen. |