Title: Clorindione
CAS Registry Number: 1146-99-2
CAS Name: 2-(4-Chlorophenyl)-1H-indene-1,3(2H)-dione
Additional Names: 2-(p-chlorophenyl)-1,3-indandione; 2-(4-chlorophenyl)indan-1,3-dione; chlophenadione
Manufacturers' Codes: G-25766; MG-2552
Trademarks: Indaliton (Geigy)
Molecular Formula: C15H9ClO2
Molecular Weight: 256.68
Percent Composition: C 70.19%, H 3.53%, Cl 13.81%, O 12.47%
Literature References: Prepn: Cavallini et al., Farmaco Ed. Sci. 10, 710 (1955); GB 748251 (1956 to Geigy). Pharmacokinetics: Danek, Pogonowska-Wala, Pol. J. Pharmacol. Pharm. 25, 307 (1973), C.A. 79, 111540b (1973). Toxicity study: Fontaine et al., Med. Pharmacol. Exp. 17, 497 (1967).
Properties: Dark red needles from alcohol, pale yellow needles from dil acetic acid, mp 145-146°. Practically insol in water. Sol in organic solvents except petr ether. LD50 orally in mice: 1220 mg/kg (Fontaine).
Melting point: mp 145-146°
Toxicity data: LD50 orally in mice: 1220 mg/kg (Fontaine)
Therap-Cat: Anticoagulant.
Keywords: Anticoagulant. |